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Posters - aNATOMIC pATHOLOGY


The content available in this section includes full-color posters and abstracts of experiments that run the gamut of ChemImage technology solutions in action. Please use the tabs below to search articles and publications by lines of business.
 
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Raman Imaging technique for prostate cancer prognostication: a feasibility study (PDF 400KB)
This study evaluated whether Raman molecular imaging (RMI) can be used to differentiate GS7 PC that subsequently progress (PROG) from those that have no evidence of desease (NED) after 5 years. Raman images were generated from unstained sections of 10 PROG patients and 10 NED patients. Measurements derived from RMI of tissue samples were analyzed using multivariate techniques established in analytical spectroscopy.
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Separation of Invasive Lobular from Ductal Carcinoma of the Breast Using Raman Molecular Imaging (PDF 772 KB)
Distinguishing invasive ductal carcinoma (IDC) from invasive lobular carcinoma (ILC) can occasionally be difficult. E-cadherin immunohistochemical (IHC) staining is helpful in distinguishing between these two carcinomas. Raman Molecular Imaging (RMI) is an analytical tool employed in many industrial applications due to its high molecular specificity and reagentless capability
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Diagnostic Utility of Raman Molecular Imaging (RMI) in Separating Renal Oncocytoma from Chromophobe Renal Cell Carcinoma (PDF 697 KB)
Raman Molecular Imaging (RMI), a technique used primarily in chemical analysis, is based on the scattering of laser light. We applied RMI as a reagentless tissue imaging approach to the analysis of pathology specimens
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Hyperspectral Fluorescence Bioimaging (PDF 1 MB)
The fluorescence emission profile of biological samples was examined using hyperspectral Fluorescence Chemical Imaging in which each pixel gives an associated spectrum.
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Raman Molecular Imaging in Application to Bladder Cancer Diagnosis (PDF 665 KB)
In 2005, 63,200 new cases of bladder cancer were diagnosed; 13,200 of these patients died. Currently, accurate and early diagnosis is not possible using cytological specimens and histochemistry staining, necessitating invasive cystoscopy and biopsy. The ability to detect Transitional Cell Carcinoma non-invasively at an early stage will lead to a significant decrease in morbidity and mortality from this disease.
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Raman Molecular Imaging: A Tool For Investigating Biological Systems (PDF 318 KB)
Chemical Imaging is a powerful tool combining digital imaging and molecular spectroscopy to yield a picture of the molecular specific components of a complex sample.
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Raman Spectroscopy To Predict Prostate Cancer Death After Radical Retropubic Prostatectomy (PDF 359 KB)
Raman spectroscopy is a measurement technique that utilizes molecular-specific, inelastic scattering of light to interrogate biological tissue. Our objective was to determine if it could add clinically useful information to prostate cancer diagnosis and identify those that progress to metastatic disease.

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