Digital Pathology Application

Traditional pathological evaluation of tissues and cells is a relatively subjective evaluation of spatially complex stained tissue samples. Accurate interpretation of pathology specimens is very challenging for a number of tissue and disease types. Accuracy is important because treatment decisions are made based on the evaluation of tissue by a pathologist.

ChemImage’s Raman Molecular Imaging (RMI) approach enables objective assessment of tissues without the use of stains or reagents.

Why Use RMI for This Application?

• Molecular specificity
• High sensitivity to subtle molecular differences
• Measurement of Raman signals from the molecular constituents of a sample without reagents
• Measurements which are spatially localized within a given sample
  

Raman molecular images are acquired from tissue samples illuminated by a laser in a microscope. The images are analyzed using chemometric based classification algorithms to objectively classify the sample in terms of disease state.

Want to know more? Download the ChemImage white paper: "Spectroscopic Pathology"

Prostate Cancer Histology (Figure 1) and Prostate Cancer Histology
Fused with a Raman Molecular Image (Figure 2)

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